Table 5

Multivariate Cox regression analysis of variables associated with death after listing for liver transplantation in all patients with refractory ascites

Cox regression analysisCompeting risk Cox regression analysis
Outcome death (censored at transplant)Outcome death
HR95% CIp ValueHR95% CIp Value
MELD score1.111.01 to 1.210.0240.990.92 to 1.060.723
Hyponatraemia2.451.07 to 5.640.0351.390.68 to 2.820.367
Hepatocellular carcinoma0.320.07 to 1.460.1410.800.27 to 2.400.689
Previous variceal haemorrhage0.500.17 to 1.400.1860.510.22 to 1.180.116
Prophylactic antibiotics0.640.27 to 1.560.3290.390.17 to 0.900.027
NSBB0.460.32 to 0.980.0450.490.25 to 0.960.038
  • p Value in bold indicates statistical significance.

  • In the competing risk Cox regression analysis, the only variable associated with the outcome transplant was MELD (adjusted HR 1.10; 95% CI 1.04 to 1.17, p=0.001) (model not shown).

  • Reference group (relative risk 1.00): no hyponatraemia, no hepatocellular carcinoma, no previous variceal haemorrhage, no prophylactic antibiotics and no NSBB.

  • MELD, model for end-stage liver disease; NSBB, non-selective β-blockers.