Table 5

Cost-effectiveness studies of interventions aimed to enhance screening acceptance

StudySettingType of studyType of interventionIncremental cost-effectiveness
Sequist et al141Opportunistic screeningRCTMailing including tailored letter, educational brochure and faecal occult blood test kit$94 per additional screenee
Davis T et al142Opportunistic screeningRCT1. Enhanced usual care
2. Literacy-informed education of patients
3. Education plus nurse support
2 vs 1: $250 per additional screenee
3 vs 1: $1337 per additional screenee
Davis T et al122Opportunistic screeningRCT1. An enhanced version of usual care with FOBT kit with a stamped envelope
2. A literacy-informed educational intervention
3. A nurse manager strategy
2 vs 1: –
3 vs 1: $2450 per additional screenees
Misra et al143Opportunistic screeningRCT1. No intervention
2. Web-based intervention
3. Tailored intervention
2 vs 1: $2602 per additional screenee
3 vs 2: dominated
Shankaran et al144Opportunistic screeningRCTPhysician offices assigned to usual care or to a series of visits from trained physician educators$21 124 per percentage point increase in CRC screening rate
Elkin et al145Opportunistic screeningRCTPatient-navigator programme$200–$700 per additional colonoscopy
Smith et al146Opportunistic screeningRCTAutomated telephone calls$40 per additional screenee
Whyte et al147PopulationModel simulationAwareness campaign£13 496 per quality-adjusted life-year
  • CRC, colorectal cancer; FOBT, faecal occult blood test; RCT, randomised controlled trial.