Table 3

Multivariate Cox regression analysis of variables associated with death after listing for liver transplantation in all patients with ascites

 Cox regression analysisCompeting risk Cox regression analysis
Outcome death (censored at transplant)Outcome deathOutcome transplant
HR (95% CI)p ValueHR (95% CI)p ValueHR (95% CI)p Value
MELD score1.12 (1.07 to 1.18)<0.0011.01 (0.97 to 1.06)0.6451.04 (1.01 to 1.07)0.017
Hyponatraemia2.52 (1.59 to 4.00)<0.0011.80 (1.15 to 2.82)0.0100.87 (0.64 to 1.17)0.350
Hepatocellular carcinoma0.64 (0.27 to 1.51)0.3090.51 (0.22 to 1.16)0.1081.85 (1.26 to 2.71)0.002
Previous variceal haemorrhage0.80 (0.49 to 1.34)0.3990.79 (0.47 to 1.34)0.3831.11 (0.84 to 1.47)0.461
Prophylactic antibiotics0.52 (0.29 to 0.94)0.0310.48 (0.27 to 0.85)0.0131.55 (1.17 to 2.06)0.003
NSBB0.53 (0.34 to 0.84)0.0070.70 (0.45 to 1.10)0.1191.21 (0.92 to 1.59)0.172
  • p Value in bold indicates statistical significance.

  • Reference group (relative risk 1.00): no hyponatraemia, no hepatocellular carcinoma, no previous variceal haemorrhage, no prophylactic antibiotics and no NSBB.

  • MELD, model for end-stage liver disease; NSBB, non-selective β-blockers.