Clinical and demographic characteristics of participants
| H (n=30) | IBS-D (n=49) | p Value | |
|---|---|---|---|
| Gender, F:M | 11:19 | 33:16 | 0.015* |
| Age, years | 29 (21–64) | 35 (18–63) | 0.094 |
| Intensity of abdominal pain, score | 0 | 45.4±25.3 | – |
| Frequency of abdominal pain, number of days | 0 | 5 (2–10) | – |
| Bowel movements (n) | 1 (0.5–2.0) | 4 (1.0–12) | <0.0001** |
| Stool form, Bristol Score | 3.5 (2.0–4.5) | 6 (4.5–7.0) | <0.0001** |
| Dyspepsia | 0 | 31/49 | – |
| Holmes–Rahe Scale | 105 (55–267) | 140 (20–889) | 0.281 |
| Cohen Scale | 17 (6–37) | 26 (9–46) | <0.0001** |
| Beck's Index | 1(0–9) | 10 (0–36) | <0.0001** |
| Respiratory atopy | 16/30 | 23/49 | 1 |
Values represent the median (range) or mean±SD.
p Values considered significant are shown in bold. p Value adjusted (false discovery rate): *<0.05; **<0.001.
F, female; M, male; H, healthy subjects; IBS-D, diarrhoea-predominant IBS.