Table 6

Reproducibility of items assessing epithelial injury

 Variance componentsICC (95% CI)*
ImageReaderInteractionResidualIntraraterInter-rater
GS—crypt destruction0.380.110.190.430.61 (0.53 to 0.68)0.34 (0.22 to 0.44)
GS—erosion or ulceration1.260.200.300.490.78 (0.71 to 0.84)0.56 (0.43 to 0.67)
MRS—erosion or ulceration0.100.040.040.090.67 (0.59 to 0.75)0.37 (0.26 to 0.50)
MRS—surface epithelial integrity0.630.080.090.320.71 (0.62 to 0.79)0.56 (0.42 to 0.67)
MRS—mucin depletion0.460.000.080.300.64 (0.55 to 0.70)0.55 (0.45 to 0.63)
Surface epithelium0.860.350.261.020.59 (0.50 to 0.67)0.35 (0.24 to 0.45)
Harpaz index0.640.150.150.450.68 (0.58 to 0.75)0.46 (0.33 to 0.58)
Granulomas0.000.010.070.090.49 (0.11 to 0.74)0.01 (0.00 to 0.07)
  • *Values represent ICCs.

  • GS, Geboes score; ICC, interclass correlation coefficient; MRS, modified Riley score.