Table 5

Comparison of acute kidney injury (AKI) and acute-on-chronic liver failure (ACLF) classifications to predict 28-day and 90-day mortality

AKIACLF at enrolmentACLF at 48 hAKI vs ACLF at enrolmentAKI vs ACLF at 48 hACLF at enrolment vs ACLF at 48 h
AUCROC*p Value
 28-day0.68 (0.62 to 0.73)0.77 (0.71 to 0.82)0.84 (0.80 to 0.89)0.0049<0.00010.0021
 90-day0.62 (0.57 to 0.66)0.72 (0.67 to 0.77)0.77 (0.73 to 0.82)<0.0001<0.00010.0092
C-index†p Value
 28-day0.66 (0.61 to 0.71)0.74 (0.69 to 0.79)0.81 (0.76 to 0.85)0.09<0.00010.0004
 90-day0.61 (0.57 to 0.65)0.69 (0.65 to 0.73)0.74 (0.70 to 0.77)0.0028<0.00010.0002

  • Values in parentheses are 95% CIs.

  • *Transplant-free mortality.

  • †Mortality considering transplantation as competing event.

  • AUCROC, area under the curve of the receiving operating characteristic.