Table 1

Sensitivity, specificity, PPV, NPV, accuracy, youden index (J=Se+Sp-1) of AFP, DCP and HCCR-1 when combined

Serum markerSensitivity (%)Specificity (%)PPV (%)NPV (%)Accuracy (%)Youden indexAUC
AFP65.4%80.2%58.6%84.4%75.8%0.4560.791
DCP44.3%86.7%58.7%78.4%74.0%0.310.678
HCCR-141.6%87.4%58.6%77.7%73.7%0.290.643
AFP+DCP67.7%82.9%62.8%85.7%78.3%0.5060.824
AFP+HCCR-175.2%75.8%57.1%87.7%75.6%0.510.830
DCP+HCCR-155.9%84.7%61.0%81.8%76.1%0.4060.746
AFP+DCP+HCCR-175.4%79.3%60.8%88.3%78.1%0.5470.891