Second validation phase: pooled overall and dichotomised diagnostic accuracy of optical diagnosis
| Accuracy all lesions (95% CI) | Accuracy diminutive lesions (95% CI) | Accuracy small lesions (95% CI) | |
|---|---|---|---|
| Overall analysis With high confidence | 0.76 (0.72 to 0.80) | 0.74 (0.69 to 0.79) | 0.81 (0.75 to 0.88) |
| 0.84 (0.81 to 0.88) | 0.83 (0.79 to 0.88) | 0.86 (0.80 to 0.93) | |
| SSA/P versus non-SSA/P With high confidence | 0.87 (0.84 to 0.90) | 0.86 (0.82 to 0.90) | 0.88 (0.83 to 0.94) |
| 0.91 (0.88 to 0.94) | 0.91 (0.87 to 0.94) | 0.91 (0.85 to 0.96) | |
| AD versus non-AD With high confidence | 0.83 (0.80 to 0.87) | 0.81 (0.77 to 0.85) | 0.89 (0.84 to 0.94) |
| 0.90 (0.87 to 0.93) | 0.88 (0.84 to 0.92) | 0.93 (0.89 to 0.98) | |
| Neoplastic lesions versus HP With high confidence | 0.82 (0.79 to 0.86) | 0.81 (0.77 to 0.85) | 0.85 (0.80 to 0.92) |
| 0.89 (0.85 to 0.92) | 0.88 (0.84 to 0.92) | 0.90 (0.84 to 0.95) |
AD, adenoma; HP, hyperplastic polyp; SSA/P, sessile serrated adenoma/polyp.