Patient | Age | Sex | SOT | Steroid* | Proliferation inhibitors* | Calcineurin inhibitors* | mTOR inhibitors* | Treatment for HEV infection* | ALT (U/L) | AST (U/L) | Bilirubin (µmol/L) | HEV genotype |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Patient #1 | 61 | m | Heart, liver | Prednisolone | Tacrolimus | Everolimus | Ribavirin | 283 | 296 | 13 | 3c | |
Patient #2 | 39 | f | Liver, kidney stem cells, lung | Prednisolone | Mycophenolate mofetil | Tacrolimus | Everolimus, sirolimus | Ribavirin | 247 | 121 | 8 | 3c |
Patient #3 | 52 | f | Heart, lung | Prednisolone | Mycophenolic acid | Tacrolimus, ciclosporine | Ribavirin | 42 | 42 | 17 | 3e | |
Patient #4 | 18 | f | Kidney | Tacrolimus | Everolimus | Ribavirin | 294 | 138 | 6 | 3c | ||
Patient #5 | 45 | f | Kidney | Prednisone | Mycophenolic acid | Everolimus | Ribavirin | 374 | 139 | 9 | 3c | |
Patient #6 | 60 | m | Heart | Prednisone | Azathioprine | Ciclosporine | Ribavirin | 108 | 68 | 15 | 3c | |
Patient #7 | 70 | m | Heart | Prednisone | Azathioprine | Ciclosporine | Everolimus< | Ribavirin | 165 | 91 | 10 | 3c |
Patient #8 | 14 | m | Liver | Prednisolone | Mycophenolate mofetil | Tacrolimus | Ribavirin | 354 | 168 | 41 | 3f | |
Patient #9 | 35 | m | Multilocular fibrosis | Prednisone | Sirolimus | Ribavirin | 473 | 296 | n.d. | 3c | ||
Patient #10 | 47 | m | Liver | Prednisolone | Ciclosporine | Reduction of immunosuppression | 78 | 78 | 45 | 3c | ||
Patient #11 | 65 | m | Liver | Prednisolone | Mycophenolate mofetil | Tacrolimus | Reduction of immunosuppression | 43 | 30 | 14 | 3f | |
Patient #12 | 47 | m | Kidney | Prednisolone | Mycophenolate mofetil | Tacrolimus | Reduction of immunosuppression | 359 | 171 | 16 | 3f |
Clinical parameter represents situation of first deep-sequencing samples drawn.
*Adjusted individually over time.