Table 2

Crude analysis for factors associated with the presence of significant fibrosis (F2–4) in the training set, in The Gambia

Factors*No or mild fibrosis
n=82
Significant
fibrosis or more n=53
Crude p value†
Age (years)36±1035±110.7
Male sex, n (%)58 (71)47 (89)0.02
AST (IU/L)39±2262±610.01
ALT (IU/L)37±2564±790.007
ALP (IU/L)97±44112±690.1
GGT (IU//L)35±2172±55<0.001
Albumin (g/L)43±441±110.003
Total bilirubin (IU/L)12±517±210.1
Platelets (109/L)201±67185±1830.007
HBV DNA (log10IU/mL)6.9±7.88.5±9.30.01
  • *Continuous variables are presented as mean±SD.

  • † p Values were obtained using logarithmic transformed values except for sex.

  • ALT, alanine transaminase; ALP, alkaline phosphatase; AST, aspartate transaminase; GGT, gamma-glutamyl transpeptidase.