Table 4

Association of S267F with chronic hepatitis B (CHB) infection

Patients with CHB* (n=3801)HBsAg-seronegative controls† (n=3801)OR (95% CI)p Value
rs2296651 (S267)
GG3099 (81.53)3145 (82.74)1.00
GA665 (17.50)651 (17.13)0.96 (0.86 to 1.09)0.553
AA37 (0.97)5 (0.13)0.13 (0.05 to 0.34)<0.001
  • *Those are patients with CHB from our cohort for analyses in this work.

  • †The controls are a subset of HBsAg-seronegative individuals in the Taiwan Biobank with available S267F genotype data, which are matched according to gender and age of patients with CHB with a 1:1 ratio.

  • HBsAg, hepatitis B surface antigen.