Table 1

Univariate and multivariate Cox regression analyses of potential poor prognostic factors in gastric cancer

UnivariateMultivariate
VariableRR (95% CI)p ValueRR (95% CI)p Value
Age1.003 (0.988 to 1.017)0.7191.001 (0.987 to 1.014)0.935
Gender0.7760.481
 Male1.056 (0.727 to 1.533)1.145 (0.785 to 1.670)
 Female11
Helicobacter pylori0.211
 Positive0.850 (0.658 to 1.097)
 Negative1
Lauren0.284
 Intestinal1.205 (0.856 to 1.697)
 Non-intestinal1
Differentiation0.387
 Low1.175 (0.815 to 1.693)
 Moderate or high1
TNM stage
 I0.100 (0.043 to 0.235)<0.00010.105 (0.045 to 0.248)<0.0001
 II0.211 (0.115 to 0.385)<0.00010.215 (0.117 to 0.394)<0.0001
 III0.249 (0.163 to 0.380)<0.00010.241 (0.157 to 0.369)<0.0001
 IV11
MDGA2 methylation0.0010.005
 Yes2.004 (1.314 to 3.057)1.851 (1.208 to 2.836)
 No11
  • RR, relative risk; TNM, Tumor-Nodes-Metastasis.