Colorectal features of CRCs diagnosed in patients with SPS
| N=47 (15%) | |
|---|---|
| Age at CRC diagnosis (years), mean±SD | 53.9±12.8 |
| WHO criteria*, n (%) | |
| ▸ Criterion I | 14 (29.7%) |
| ▸ Criterion III | 19 (40.6%) |
| ▸ Criteria I+III | 14 (29.7%) |
| Tumour location, n (%) | |
| ▸ Caecum | 3 (6.4%) |
| ▸ Ascending colon | 6 (12.8%) |
| ▸ Hepatic flexure | 3 (6.4%) |
| ▸ Transverse colon | 10 (21.3%) |
| ▸ Descending colon | 1 (2.1%) |
| ▸ Sigmoid colon | 18 (38.3%) |
| ▸ Rectum | 6 (12.8%) |
| TNM tumour stage, n (%) | |
| ▸ I | 24 (51%) |
| ▸ II | 12 (25.5%) |
| ▸ III | 6 (12.8%) |
| ▸ IV | 5 (10.7%) |
| Time at CRC diagnosis, n (%) | |
| ▸ Before SPS diagnosis | 8 (17%) |
| ▸ At the time of SPS diagnosis | 35 (74.5%) |
| ▸ During SPS surveillance | 4 (8.5%) |
*WHO criteria: (I) patients who fulfil criterion I only; (III) patients who fulfil criterion III only; (I+III): patients who fulfil both I and III criteria.
CRC, colorectal cancer; SPS, serrated polyposis syndrome; TNM, tumour, node, metastases.