Table 3

Colorectal features of CRCs diagnosed in patients with SPS

N=47 (15%)
Age at CRC diagnosis (years), mean±SD53.9±12.8
WHO criteria*, n (%)
 ▸ Criterion I14 (29.7%)
 ▸ Criterion III19 (40.6%)
 ▸ Criteria I+III14 (29.7%)
Tumour location, n (%)
 ▸ Caecum3 (6.4%)
 ▸ Ascending colon6 (12.8%)
 ▸ Hepatic flexure3 (6.4%)
 ▸ Transverse colon10 (21.3%)
 ▸ Descending colon1 (2.1%)
 ▸ Sigmoid colon18 (38.3%)
 ▸ Rectum6 (12.8%)
TNM tumour stage, n (%)
 ▸ I24 (51%)
 ▸ II12 (25.5%)
 ▸ III6 (12.8%)
 ▸ IV5 (10.7%)
Time at CRC diagnosis, n (%)
 ▸ Before SPS diagnosis8 (17%)
 ▸ At the time of SPS diagnosis35 (74.5%)
 ▸ During SPS surveillance4 (8.5%)
  • *WHO criteria: (I) patients who fulfil criterion I only; (III) patients who fulfil criterion III only; (I+III): patients who fulfil both I and III criteria.

  • CRC, colorectal cancer; SPS, serrated polyposis syndrome; TNM, tumour, node, metastases.