Clinical management of patients with serrated polyposis syndrome
| No. of patients who received clearing of all relevant lesions | 403 |
| Time from diagnosis up to clearing (months); median (IQR) | 1.5 (0–8.7) |
| No. of patients who received surgery during clearing; n (%) | 95 (23.6) |
| Reason surgery during clearing; n (%) | |
| CRC | 56 (58.9) |
| Polyp burden | 30 (31.6) |
| Unresectable polyp | 8 (8.4) |
| Perforation due to polypectomy | 1 (1.1) |
| No. of needed clearing colonoscopies; median (IQR)* | 2 (1–3) |
| No. of patients who received surveillance after clearing of all polyps | 260 |
| Follow-up time since clearing of all polyps (years); median (IQR)† | 3.2 (1.6–5.7) |
| No. of colonoscopies during surveillance; median (IQR)† | 2 (1–4) |
| Interval between surveillance colonoscopies (years); median (IQR)† | 1.2 (1.0–1.6) |
| No. of patients who received surgery during surveillance; n (%) | 11 (4.2) |
| Reason surgery during surveillance; n (%) | |
| CRC | 1 (9.1) |
| Polyp burden | 5 (45.4) |
| Unresectable polyp | 4 (36.4) |
| Perforation due to polypectomy | 1 (9.1) |
| Overview of detected polyps during surveillance per patient† | |
| No. of SPs; median (IQR) | 7 (2–18) |
| No. of SPs proximal to the rectosigmoid; median (IQR) | 2 (0–7) |
| No. of large SPs; median (IQR) | 0 (0–1) |
| Patients with at least 1 SP ≥10 mm; n (%) | 70 (26.9) |
| No. of adenomas; median (IQR) | 0 (0–2) |
| Patients with at least 1 adenoma; n (%) | 122 (46.9) |
| Patients with at least 1 SP ≥10 mm proximal to the rectosigmoid; n (%) | 65 (25.0) |
| Patients with at least 1 SP-containing dysplasia; n (%) | 16 (6.2) |
| Patients with at least 1 advanced adenoma; n (%) | 20 (7.7) |
*Referred to the 308 patients who did not receive surgery during clearing.
†Referred to the 260 patients who received surveillance after clearing of all polyps.
CRC, colorectal cancer; SPs, serrated polyps.