Table 1

Demographic, clinical characteristics and laboratory results of the study cohort

VariablesHealthy/non-excessive drinkers (n=45)Alcoholics with or without recent drinking (n=300)p Value*Alcoholics—stratified by recent drinking statusp Value†
Alcoholics without recent drinking‡ (n=160)Alcoholics with recent drinking§ (n=140)
Age (years)31±737.5±0.60.000136±1139±110.001
Gender—male (n, %)30 (67)223 (74.3)0.28118 (74)105 (75)0.53
Race (white, %)39 (87)249 (83)0.95131 (82)118 (84)0.39
Height (cm)175.6±10.2175.9±0.50.83175.3±8.9176.6±9.10.44
Weight (kg)87.1±16.386.8±1.00.9486.5±19.187.2±16.10.94
BMI (kg/m2)28.1±3.828.1±0.30.9628.1±5.828.0±5.10.98
Total drinks in the last 30 days4.0±5.4196.8±10.50.000194.2±94.9314.0±188.20.001
Number of days drinking out of 30 days2.5±3.516.8±0.50.000110.3±5.624.3±2.80.001
Total bilirubin (mg/dL)0.5±0.20.7±0.020.0020.6±0.30.8±0.50.001
AST (U/L)18.4±7.031.9±1.60.00128.4±21.436.0±33.60.001
ALT (U/L)33.4±5.446.6±1.40.00144.8±21.948.7±28.40.01
Albumin (g/dL)4.2±0.33.8±0.020.00013.9±0.43.6±0.40.001
Total protein (g/dL)7.8±0.57.1±0.20.177.0±0.87.1±5.40.39
Haemoglobin (g/dL)14.4±1.513.9±0.090.0814.0±1.613.8±1.60.13
Platelet counts (×103/µL)237±64.6231.1±4.30.58237±76.1223.1±70.60.18
White blood cell counts (WBC, ×103/µL)6.6±1.57.0±0.120.256.7±1.77.3±2.30.04
Percentage of neutrophils to WBC60.7±7.972.7±0.780.000167.0±13.780.0±9.80.0001
Percentage of monocytes to WBC6.7±2.09.2±0.180.00018.8±3.19.7±3.00.0001
Percentage of lymphocytes to WBC29.6±7.115.2±0.730.000120.6±12.99.3±9.20.0001
Neutrophil counts (×103/µL)3.9±0.95.1±0.110.00014.5±1.45.7±1.60.0001
Monocyte counts (×103/µL)0.4±0.10.6±0.010.00010.6±0.20.7±0.30.0001
Lymphocyte counts (×103/µL)1.9±0.61.2±0.050.00011.7±0.70.6±0.60.0001
  • Data are presented as mean±SD. *p Value in this column was obtained from t-test analysing two groups of healthy controls and total alcoholics.

  • †p Value in this column was obtained from analysis of variance test analysing three groups of healthy controls, alcoholics with or without recent excessive drinking.

  • ‡Excessive drinkers with last drink ≥10 days before the enrolment.

  • §Excessive drinkers with last drinks within 10 days before the enrolment.

  • BMI, body mass index; WBC, white blood cell.