Performance of ultrasound scanning and liver function tests according to pre-test probability34
| Test (cut-off) | Summary sensitivity (95% CI) | Summary specificity (95% CI) | Pre-test probability | Positive post-test probability (95% CI) | Negative post-test probability (95% CI) |
|---|---|---|---|---|---|
| Ultrasound | 0.73 (0.44 to 0.90) | 0.91 (0.84 to 0.95) | 0.095 | 0.45 (0.31 to 0.60) | 0.03 (0.01 to 0.07) |
| 0.408 | 0.85 (0.75 to 0.91) | 0.17 (0.08 to 0.33) | |||
| 0.658 | 0.94 (0.89 to 0.97) | 0.37 (0.20 to 0.58) | |||
| Bilirubin (>22.23 μmol/L) | 0.84 (0.64 to 0.94) | 0.91 (0.86 to 0.94) | 0.095 | 0.49 (0.38 to 0.59) | 0.02 (0.01 to 0.04) |
| Bilirubin (>twice the normal limit) | 0.42 (0.22 to 0.63) | 0.97 (0.95 to 0.99) | 0.095 | 0.63 (0.41 to 0.81) | 0.06 (0.04 to 0.08) |
| Alkaline phosphatase (>125 IU/L) | 0.92 (0.74 to 0.99) | 0.79 (0.74 to 0.84) | 0.095 | 0.32 (0.26 to 0.38) | 0.01 (0.00 to 0.04) |
| Alkaline phosphatase (>twice the normal limit) | 0.38 (0.19 to 0.59) | 0.97 (0.95 to 0.99) | 0.095 | 0.61 (0.38 to 0.80) | 0.06 (0.05 to 0.08) |