Table 4

Significant correlations between bacterial genera and symptoms, H2 production and urine metabolome in faecal samples from patients with IBS after high or low FODMAP diet (Δ(P1−P0))

Histamine↓pHBA↑Aza↑H2Sx↓
Actinobacteria
Bacteroidetes
Firmicutes + * *
Proteobacteria
Verrucomicrobia +
Adlercreutzia * +
Actinomyces + +* +
Uncl. Bacteroidetes
Uncl. Bacteroidales
Odoribacter −*
Parabacteroides −*
Uncl. Porphyromonadaceae +
Prevotella −*
Alystipes
Granulicatella +
Lactococcus
Lactobacillus +
Uncl. Clostridiales +
Uncl. Ruminococcaceae + −*
Ruminococcus +
Eubacterium +
Clostridium (Ruminococcaceae) +
Bacteroides (Ruminococacceae)
Uncl. Lachnospiraceae
Lachnobacterium −*
Lachnospira +
Roseburia −*
Uncl. Erysipelotrichaceae
Holdemania
Escherichia
Bilophila −*
A. muciniphila + *
  • The grey font indicates significant correlations for low FODMAP patients and the black font indicates significant correlations for high FODMAP patients.

  • *Indicates a statistically significant linear regression.

  • Aza, azelaic acid; FODMAP, fermentable oligosaccharides, disaccharides and mono-saccharides and polyols; H2, hydrogen gas; pHBA, p-hydroxybenzoic acid; Sx, symptoms.