| Year of presentation | 1987–2006 | 2007–2016 | 1987–2016 |
|---|---|---|---|
| Number | 202 | 143 | 345 |
| Follow-up time (yrs)^ | 13 (0.0–28.8) | 4.5 (0.0–10) | 8 (0.0–29) |
| Age at presentation^ | 57 (2.5–87) | 60 (14–85) | 58.0 (2.5–87) |
| Cirrhosis at presentation (%)* | 64/198 (32) | 27/140 (19) | 91/338 (27) |
| Decompensation at presentation (%) | 33/198 (17) | 17/138 (12) | 50/236 (15) |
| SMR over 1st decade (all cause death/transplant)* | 2.28 (1.6–2.9) | 1.27 (0.57–1.98) | 1.77 (1.4–21) |
| Total deaths or transplants | 93 | 13 | 106 |
| Number transplants/liver deaths | 6/24 | 2/4 | 8/28 |
| 5 year death/transplant rate: All-cause (%(SEM)) Liver (%(SEM)) | 15(2) 8 (2) | 11(3) 4 (2) | 13 (2) 7 (1) |
^ median(range), *p<0.01 for 87–06 vs 07–16
All-cause death/transplant rate in those presenting since 2007 was lower compared to 1987–2006 (p=0.155 by Log-Rank test but 0.041 by Cox regression analysis, along with age and baseline cirrhosis and decompensation). SMR (over the first decade of follow up) was lower in those presenting since 2007 (Table 1). Corresponding liver death/transplant rates did not differ.