Table 4

Positivity of FIT (cut-off 20 µg Hb/g faeces) and gFOBt by screening episode and Hub

Prevalent
(first-time invitees)
Prevalent
(previous non-responders)
Incident
(previous responders)
Total
Adequately screenedPositiveAdequately screenedPositiveAdequately screenedPositiveAdequately screenedPositive
FIT
 Midlands and North West18141221315150934080712 4691079
6.73%11.41%8.64%8.65%
 Southern2119125151614111 06378214 6981048
5.90%9.30%7.07%7.13%
 Total3933247283129120 403158927 1672127
6.28%10.28%7.79%7.83%
gFOBt
 Midlands and North West40 55670918 088518250 3983845309 0425072
1.75%2.86%1.54%1.64%
 Southern47 51581322 251684289 1375006358 9036503
1.71%3.07%1.73%1.81%
 Total88 071152240 3391202539 5358851667 94511 575
1.73%2.98%1.64%1.73%
OR (95% CI) (FIT vs gFOBt)
 Midlands and North West4.05 (3.32 to 4.94)4.37 (3.61 to 5.29)6.06 (5.60 to 6.56)5.68 (5.30 to 6.08)
 Southern3.60 (2.97 to 4.37)3.23 (2.68 to 3.91)4.32 (3.99 to 4.67)4.16 (3.89 to 4.45)
 Total3.81 (3.32 to 4.38)3.73 (3.26 to 4.27)5.06 (4.79 to 5.35)4.82 (4.59 to 5.05)
  • FIT, faecal immunochemical test; gFOBt, guaiac-based faecal occult blood test; Hb, haemoglobin.