Table 1

Number of cases, observation years and age at inclusion stratified on country of origin, genetic variant and gender

Observation yearsAge at inclusion
NumberTotalMean (range)95% CI of meanMean (range)95% CI of mean
ALL127377536.1 (1–29)±0.2451.6 (21–95)±0.68
Females7184416.1 (1–29)±0.3352.7 (21–95)±0.88
Males55533426.0 (1–27)±0.3650.3 (21–91)±1.04
Grouped by country
Finland36526537.3 (1–24)±0.5053.6 (25–95)±1.25
UK1959885.1 (1–16)±0.5151.0 (21–82)±1.71
Denmark18110045.5 (1–15)±0.4952.0 (24–83)±1.70
Spain1417435.3 (1–13)±0.6051.4 (24–89)±2.08
Germany1266505.2 (1–29)±0.7345.1 (21–71)±1.88
Norway1086846.3 (1–19)±0.9255.6 (27–83)±2.20
Sweden614557.5 (1–27)±1.3152.8 (29–77)±3.11
Holland552384.3 (1–19)±1.1851.6 (22–82)±3.71
Australia352938.4 (1–26)±1.9544.9 (22–70)±3.56
Italy6457.5 (2–11)±3.4642.7 (33–55)±5.67
Grouped by gene and gender
path_MLH1
Females30521727.1 (1–29)±0.5552.0 (21–84)±1.42
Males28419066.7 (1–21)±0.5249.8 (23–91)±1.45
path_MSH2
Females28515025.3 (1–19)±0.4551.6 (22–83)±1.27
Males18510855.9 (1–27)±0.6547.5 (21–73)±1.56
path_MSH6
Females1096696.1 (1–19)±0.8657.6 (27–95)±2.38
Males582654.6 (1–13)±0.7557.6 (33–83)±3.44
path_PMS2
Females19683.6 (1–13)±1.4152.0 (37–68)±4.05
Males28863.1 (1–10)±0.9358.5 (27–77)±4.80