Table 2

Genes selected for validation by RT-qPCR from microarray data comparing the gene expression profile of atorvastatin-treated normal colonic epithelial cells from tumour-free versus tumour-bearing mice

Gene*	Microarray log₂ fold change	P value	RT-qPCR validation correlation†
Cxcl5	3.13	0.004	0.9
Fabp7	2.46	0.004
Ctnnb1	2.23	0.002
Pten	1.09	0.003
Tesc	−2.38	0.002
Pthlh	−1.96	0.002
Mapk11	−1.61	0.005
Igf1	−1.24	0.005

*False discovery rate for these genes was 0.379.
†Spearman rank correlation of fold change in mRNA expression determined by microarray versus RT-qPCR.
mRNA, messenger RNA; RT-qPCR, real-time quantitative PCR.