Liver aetiology table for patients with non-acute abnormal liver blood tests
| Standard liver aetiology panel | Extended liver aetiology panel | |
| Viral hepatitis | Hepatitis B surface antigen AND hepatitis C antibody (with follow-on PCR if positive) | Anti-HBc and anti-HBs hepatitis B DNA quantification of hepatitis delta in high-prevalence areas |
| Iron overload | Ferritin AND transferrin saturation | Haemochromatosis gene testing |
| Autoimmune liver disease (excluding PSC) | Anti-mitochondrial antibody, anti-smooth muscle antibody, antinuclear antibody, serum immunoglobulins | Anti-LKM antibody and coeliac antibodies (consider ANCA in the presence of cholestatic liver blood tests) |
| Metabolic liver disease | Alpha-1-antitrypsin level; thyroid function tests; caeruloplasmin (age >3 and <40 years)±urinary copper collection |
ANCA, antineutrophil cytoplasmic antibodies; LKM, liver kidney miscrosome; PCR, polymerase chain reaction; PSC, primary sclerosing cholangitis.