Final multivariate model showing predictors associated with colorectal neoplasia
| Variables | HR (95% CI) | P value |
| Cumulative inflammatory burden | ||
| Endoscopic* | 2.1 (1.5 to 2.9) | <0.001 |
| Histological* | 2.1 (1.4 to 3.0) | <0.001 |
| Macroscopic features of chronicity | ||
| Scarring only | 1.4 (0.8 to 2.4) | 0.3 |
| Tubular, featureless or shortened colon | 1.8 (1.1 to 2.9) | 0.03 |
| Postinflammatory polyps | 1.2 (0.8 to 1.8) | 0.4 |
| Colonic stricture | 3.2 (1.3 to 8.0) | 0.01 |
| Chromoendoscopy | 1.0 (0.6 to 1.7) | 1.0 |
| Primary sclerosing cholangitis | 2.3 (1.1 to 4.7) | 0.02 |
| Age (at colonoscopy) | 1.02 (1.00 to 1.04) | 0.03 |
| Average number of biopsies | 1.14 (1.08 to 1.20) | <0.001 |
| Average surveillance interval | 0.93 (0.91 to 0.96) | <0.001 |
*HR per 10-unit increase in cumulative inflammatory burden (equivalent of 10, 5 or 3.3 years of continuous mild, moderate or severe active disease, respectively). Statistically significant variables are highlighted in bold.