Comparison of significant taxa associations in patients with UC: family level and above
| Gut microbiota alterations in patients with UC (current study: FDR<0.05) | ||||
|---|---|---|---|---|
| Taxon (family and above) | Phylum (or kingdom) | Current study* | Gevers et al† | Morgan et al‡ |
| f__Methanobacteriaceae | Archea | Down | Not reported | Not reported |
| f__Actinomycetaceae | Actinobacteria | Down | Not reported | Not reported |
| f__Coriobacteriaceae | Actinobacteria | Down | Not reported | Not reported |
| p__Bacteroidetes | Up | Not reported | Not reported | |
| o__Bacteroidales | Bacteriodetes | Up | Not reported | Not reported |
| f__Porphyromonadaceae | Bacteriodetes | Not reported | Not reported | Up |
| p__Firmicutes | Down | Down | Not reported | |
| f__Enterococcaceae | Firmicutes | Up | Not reported | Not reported |
| f__Lactobacillaceae | Firmicutes | Up | Not reported | Not reported |
| c__Clostridia | Firmicutes | Down, in lower taxonomic levels | Down | Not reported |
| o__Clostridiales | Firmicutes | Down, in lower taxonomic levels | Down | Not reported |
| f__Mogibacteriaceae | Firmicutes | Down | Not reported | Not reported |
| f__Christensenellaceae | Firmicutes | Down | Not reported | Not reported |
| f__Clostridiaceae | Firmicutes | Down, in lower taxonomic levels | Down, in lower taxonomic levels | Not reported |
| f__Dehalobacteriaceae | Firmicutes | Down | Not reported | Not reported |
| f__Lachnospiraceae | Firmicutes | Within the family genera, both going up and down | Down, in lower taxonomic levels | Not reported |
| f__Ruminococcaceae | Firmicutes | Down, in lower taxonomic levels | Down | Not reported |
| f__Veillonellaceae | Firmicutes | Not reported | Up | Not reported |
| f__Erysipelotrichaceae | Firmicutes | Down, in lower taxonomic levels | Not reported | Down, in lower taxonomic levels |
| f__Streptococcaceae | Firmicutes | Not reported | Not reported | Down |
| p__Proteobacteria | Up | Not reported | Not reported | |
| c__Betaproteobacteria | Proteobacteria | Up | Not reported | Not reported |
| o__Burkholderiales | Proteobacteria | Up | Not reported | Not reported |
| p__Tenericutes | Down | Not reported | Down | |
| c__Mollicutes | Tenericutes | Down | Not reported | Down |
| f__Anaeroplasmataceae | Tenericutes | Not reported | Not reported | Down |
| f__Verrucomicrobiaceae | Verrucomicrobia | Down, in lower taxonomic levels | Not reported | Not reported |
k__, kingdom; p__; phylum; c__ , class; o__ , order; f__, family.
*313 patients with IBD including 188 patients with Crohn's disease (CD); 582 healthy controls; stool only.
†Cell Host Microbe 2014; 447 patients with CD; 221 controls; stool and biopsy.
‡Genome Biology 2012; 204 patients with IBD including 121 patients with CD and 27 controls; stool and biopsy.
§Gastroenterology 2010; 40 twin pairs concordant or discordant for CD/UC (23 CD pairs, 15 UC pairs, 2 healthy pairs).
FDR, false discovery rate.