Table 5

Accuracy of significant lesion characteristics for prediction of dysplasia

Lesion characteristicSensitivity
(95% CI)
Specificity
(95% CI)
PPV
(95% CI)
NPV
(95% CI)
Accuracy
(95% CI)
Proximal location*59 (49 to 68)56 (52 to 61)20 (15 to 25)88 (83 to 91)58 (51 to 65)
Loss of innominated lines56 (46 to 66)56 (52 to 61)19 (15 to 24)87 (84 to 91)57 (49 to 64)
Protruding lesion†56 (46 to 66)68 (63 to 72)25 (19 to 31)89 (86 to 92)62 (55 to 70)
Neoplastic Kudo pit pattern‡32 (22 to 42)92 (89 to 94)43 (30 to 56)87 (84 to 91)63 (55 to 71)
Combination of all features10 (4 to 16)99.8 (98 to 99.9)90 (56 to 99)86 (83 to 88)85 (82 to 89)
  • *Proximal colon: proximal to splenic flexure (transverse and ascending segments).

  • †Protruding lesion: includes Paris I-p classification (sessile and pedunculated).

  • ‡Neoplastic pit pattern: Kudo III, IV and V.

  • NPV, negative predictive value; PPV, positive predictive value.