Risk factors for the development of sedation-associated complications
| Variable | Selected multiple logistic regression | |||
| OR | Lower OR 95% CI | Upper OR 95% CI | P value | |
| American Society of Anesthesiologists (ASA) >2 | 2.2998 | 2.0112 | 2.6299 | <0.001 |
| Planned endoscopy, yes | 0.7413 | 0.5663 | 0.9704 | 0.029 |
| Planned, yes * Therapeutic, yes | 1.7443 | 1.0967 | 2.7743 | 0.019 |
| Duration | ||||
| <10 min (reference) | 1 | |||
| 10–30 min | 1.7613 | 1.4568 | 2.1295 | <0.001 |
| 30–60 min | 3.8314 | 2.9964 | 4.899 | <0.001 |
| >60 min | 7.8957 | 5.8194 | 10.7129 | <0.001 |
| Technique | ||||
| Oesophagogastroduodenoscopy (OGD) (reference) | 1 | |||
| Colonoscopy | 0.6369 | 0.5404 | 0.7507 | <0.001 |
| Enteroscopy | 0.9925 | 0.6596 | 1.4934 | 0.971 |
| Endoscopic ultrasound | 0.4397 | 0.3161 | 0.6118 | <0.001 |
| Endoscopic retrograde cholangiopancreatography (ERCP) | 0.769 | 0.616 | 0.9601 | 0.02 |
| Sedation agents | ||||
| Midazolam (alone) (reference) | 1 | |||
| Propofol (alone) | 0.7509 | 0.5816 | 0.9696 | 0.028 |
| Propofol and midazolam | 1.0049 | 0.7537 | 1.3398 | 0.974 |
| Midazolam and opiate | 1.501 | 1.1144 | 2.0216 | 0.008 |
| Other sedation | 1.5458 | 1.1087 | 2.1552 | 0.01 |
| Nurse-administered propofol sedation (NAPS), yes | 1.4034 | 1.1928 | 1.6513 | <0.001 |
| Physician, yes | 2.1288 | 1.7908 | 2.5305 | <0.001 |
| Aaesthetist, yes | 4.4639 | 2.6522 | 7.5131 | <0.001 |
| Type | ||||
| Basic (reference) | 1 | |||
| Special | 0.7563 | 0.6257 | 0.9142 | 0.004 |
| Maximum | 1.6118 | 1.3485 | 1.9265 | <0.001 |