Table 3

Crohn's disease overall disease severity index

AttributeLevelScore
Mucosal lesionsNo mucosal lesions0
Small mucosal lesions as confirmed by MRI or endoscopy6
Large or deep mucosal lesions as confirmed by MRI or endoscopy16
FistulaNo fistula at the time of clinic visit0
Has fistula at the time of clinic visit11
Perianal abscessNo perianal abscess at the time of clinic visit0
Has perianal abscess at the time of clinic visit10
Intestinal resectionsNo intestinal resections0
At least one intestinal resection <40 cm2
At least one intestinal resection ≥40 cm7
StomaNo stoma at the time of clinic visit0
Has stoma at the time of clinic visit7
Disease extentLimited disease (<40 cm ileal involvement, or absence of pancolitis)0
Extensive disease (ileal involvement of at least 40 cm or presence of pancolitis)6
Frequency loose stools<10 loose stools per week0
At least 10 loose stools per week6
StrictureNo stricture at the time of visit0
Has stricture at the time of visit5
CRP levelNormal CRP levels (1–3 mg/L)0
Slightly elevated CRP levels (3–5 mg/L)2
Elevated CRP levels (above 5 mg/L)5
Biologics useHas never used biologics/immunomodulators0
Has experienced some symptom improvement with the use of biologics/immunomodulators2
Has not experienced symptom improvement with the use of biologics/immunomodulators5
Daily activity impactDisease does not significantly impact daily activities0
Disease significantly impacts daily activities5
Albumin levelNormal albumin level (>3.5 g/dL)0
Low albumin level (<3.5 g/dL)4
Anorectal symptomsNone of the following: anorectal pain, bowel urgency, incontinence, discharge, tenesmus0
At least one of the following: anorectal pain, bowel urgency, incontinence, discharge, tenesmus4
AnaemiaNot anaemic (according to WHO criteria)0
Anaemic (according to WHO criteria)4
Abdominal painInfrequent abdominal pain (less than daily)0
Daily abdominal pain3
Steroid useNo steroid use within the past year0
Has steroid use within the past year2

  • CRP, C reactive protein.