Outcome | <40 years | 40–60 years | >60 years | ||||||
---|---|---|---|---|---|---|---|---|---|
Number of deaths | HR (CI 95%)* | Number of deaths | HR (CI 95%)* | Number of deaths | HR (CI 95%)* | ||||
Severe reflux | No reflux | Severe reflux | No reflux | Severe reflux | No reflux | ||||
Men | |||||||||
All-cause mortality | 7 | 118 | 0.95 (0.43 to 2.09) | 96 | 778 | 1.02 (0.81 to 1.29) | 294 | 3563 | 0.86 (0.74 to 0.99) |
Overall cancer-specific mortality | 2 | 28 | 1.08 (0.24 to 4.81) | 35 | 314 | 1.09 (0.76 to 1.58) | 71 | 858 | 1.02 (0.77 to 1.34) |
Oesophageal adenocarcinoma-specific mortality | 0 | 0 | – | 4 | 3 | 81.73 (8.50 to 785.53) | 4 | 14 | 3.59 (0.98 to 13.20) |
Head-and-neck and lung cancer-specific mortality | 0 | 4 | – | 11 | 98 | 0.81 (0.40 to 1.64) | 20 | 201 | 1.27 (0.74 to 2.18) |
Women | |||||||||
All-cause mortality | 5 | 96 | 1.36 (0.54 to 3.45) | 52 | 589 | 1.02 (0.74 to 1.40) | 373 | 3122 | 0.93 (0.81 to 1.07) |
Overall cancer-specific mortality | 1 | 52 | 0.55 (0.07 to 4.04) | 22 | 326 | 0.77 (0.48 to 1.24) | 75 | 565 | 1.24 (0.92 to 1.66) |
Oesophageal adenocarcinoma-specific mortality | 0 | 0 | – | 0 | 4 | – | 4 | 6 | 10.49 (1.99 to 55.27) |
Head-and-neck and lung cancer-specific mortality | 0 | 5 | – | 5 | 84 | 0.80 (0.32 to 2.01) | 12 | 100 | 1.32 (0.63 to 2.77) |
*Adjusted for body mass index, tobacco smoking, alcohol consumption, physical activity, education, chronic obstructive pulmonary disease, cardiovascular diseases, diabetes and hypertension.