Table 1

Pooled prevalence of gastro-oesophageal reflux symptoms according to geographical location

Studies (n)Subjects (n)Pooled prevalence (%)95% CI (%)I2 (%)p Value for I2
All studies108460 98414.813.5–16.199.3<0.001
 North American studies1243 79415.410.7–20.999.5<0.001
 Central American studies150019.616.2–23.4N/AN/A
 South American studies624 16417.611.0–25.399.4<0.001
 European studies44218 53417.115.1–19.199.3<0.001
  Northern European studies31198 68615.513.6–17.599.2<0.001
  Southern European studies1319 84821.315.8–27.398.8<0.001
 Middle Eastern studies1386 42815.011.5–19.099.4<0.001
 Asian studies2367 10310.07.1–13.299.4<0.001
  South Asian studies5886422.111.5–35.099.4<0.001
  Southeast Asian studies1858 2397.45.0–10.199.3<0.001
 Australasian studies920 46114.112.2–16.293.5<0.001
  • N/A, not applicable, too few studies to assess heterogeneity.