Not readmitted (n=96) | Readmitted (n=27) | |
Clinical parameters | ||
Age (years) | 57.9±7.4 | 55.2±7.5 |
Gender (men/women) | 81/15 | 14/13* |
Aetiology (HCV, alcohol, HCV+alcohol, NAFLD, others) | 38/10/15/21/12 | 7/7/4/4/3 |
MELD score | 15.3±6.9 | 17.5±8.1 |
Prior hepatic encephalopathy | 35 | 14* |
Lactulose alone/any rifaximin | 15/20 | 11/3* |
SBP prophylaxis | 10 | 3 |
Proton pump inhibitors | 46 | 14 |
Non-selective beta-blockers | 39 | 10 |
Diabetes | 26 | 8 |
Infection | 23 | 15* |
Inpatient group | 34 | 17* |
Microbiota parameters | ||
Fungal Shannon index | 1.0±0.7 | 0.71±0.4* |
All Ascomycota (median relative abundance) | 76% | 98%* |
All Basidiomycota (median relative abundance) | 0% | 0.1% |
Basidiomycota/Ascomycota ratio | 0.3±0.8 | 0.06±0.10* |
Bacterial Shannon index | 1.4±0.4 | 1.3±0.6 |
All Proteobacteria (median relative abundance) | 2% | 7%* |
All Bacteroidetes (median relative abundance) | 40% | 8%* |
All Firmicutes (median relative abundance) | 39% | 45% |
MELD, model for end-stage liver disease; NAFLD, non-alcoholic fatty liver disease; SBP, spontaneous bacterial peritonitis.