Table 1

Genes selected for validation by RT-qPCR from microarray data comparing the gene expression profile of Sul/Atorva-treated adenomas versus untreated adenomas

Gene* Microarray log2 fold changeP valueRT-qPCR
validation correlation†
Hoxb13 6.740.0040.94
Rprm 5.17<0.001
Mre11a 1.550.002
Cdk1 −2.70<0.001
Cdk7 −1.75<0.001
Myc −1.83<0.001
  • *False discovery rate for these genes was ≤0.033.

  • †Spearman rank correlation of fold change in mRNA expression determined by microarray versus RT-qPCR.

  • mRNA, messenger RNA; RT-qPCR, real-time quantitative PCR.