Table 1

Comparison of taxa relative abundance in pre-PPI and post-PPI samples

Bacteria*Pre-PPI mean (SD)Post-PPI mean (SD)p Value
Phylum
Firmicutes70.70 (10.40)69.00 (10.40)0.5531
Bacteroidetes20.60 (12.30)24.00 (10.70)0.0914
Actinobacteria 4.25 (4.76) 2.35 (2.44) 0.0059
Proteobacteria2.51 (2.96)3.01 (2.55)0.2296
Verrucomicrobia1.14 (4.22)1.10 (2.80)0.7726
Euryarchaeota0.65 (1.75)0.20 (0.54)0.3242
Tenericutes0.13 (0.44)0.22 (0.71)0.2708
Cyanobacteria0.02 (0.08)0.04 (0.11)0.4591
Family
Lachnospiraceae 33.40 (20.50) 28.60 (7.70) 0.0059
Ruminococcaceae 20.50 (9.35)21.30 (7.98)0.6373
Bacteroidaceae 13.40 (10.70)14.90 (9.33)0.1961
Streptococcaceae 1.49 (1.91) 5.93 (5.30) 0.0009
Prevotellaceae 3.21 (8.23)4.09 (9.87)0.6814
Erysipelotrichaceae 4.09 (3.30) 2.74 (3.69) 0.0132
Bifidobacteriaceae 2.83 (4.39) 1.39 (2.09) 0.0275
Rikenellaceae 1.61 (1.23)2.14 (1.90)0.0914
  • Bold values indicate statistical significance at p<0.05.

  • *Table includes only the eight most commonly identified phyla and families.

  • PPI, proton pump inhibitor.