Table 2

Total obese, incidence density, unadjusted and adjusted HRs of obesity for sex, caesarean section, military rank and those prescribed histamine-2 receptor antagonists (H2RAs), proton pump inhibitors (PPIs) and antibiotics

Number of obese (%)Incidence density (per 100 person-years)Unadjusted HR (95% CI)Adjusted HR (95% CI)
PPI prescription1841 (16.6)3.851.04 (1.03 to 1.05)1.02 (1.01 to 1.03)
H2RA prescription5955 (15.1)3.641.03 (1.02 to 1.03)1.01 (1.004 to 1.02)
Antibiotic class prescriptions36 899 (15.3)3.541.26 (1.23 to 1.28)
 010 094 (11.0)2.71RefRef
 113 852 (13.3)3.171.14 (1.11 to 1.17)1.12 (1.09 to 1.15)
 210 882 (15.4)3.561.26 (1.23 to 1.30)1.23 (1.20 to 1.26)
 37457 (17.4)3.931.38 (1.34 to 1.42)1.33 (1.29 to 1.37)
 4+4708 (19.4)4.271.48 (1.43 to 1.53)1.42 (1.37 to 1.46)
Caesarean section birth14 571 (16.7)3.951.28 (1.26 to 1.31)1.26 (1.24 to 1.29)
Sex (M vs F)26 748 (15.6)3.681.26 (1.24 to 1.28)
Military rank
 Junior enlisted8976 (14.4)3.701.39 (1.33 to 1.45)1.40 (1.34 to 1.46)
 Senior enlisted28 870 (14.7)3.431.24 (1.20 to 1.27)1.23 (1.20 to 1.27)
 Junior officer8136 (12.2)2.76RefRef
 Senior officer893 (12.1)2.650.96 (0.90 to 1.03)0.96 (0.90 to 1.03)
 Other118 (15.9)3.711.30 (1.08 to 1.57)1.28 (1.06 to 1.54)
  • A significant interaction was found between sex and prescriptions for antibiotics and H2RAs. The effect of sex was adjusted through stratified Cox proportional hazards models and is presented in table 3. HRs for PPIs and H2RAs represent a unit increase in exposure level. Exposure levels were defined as 0 days, 1–30 days supply, 31–60 days supply, 61–90 days supply, 91–120 days supply, 121–150 days supply, 151–180 days supply and >180 days supply.

  • F, female; M, male.