ESD cases performed, surgeries and costs by strategy
| Outcome | Number per 1000 patients* (N) | |||
| WF-EMR | S-ESD (base case) | S-ESD (JGES)† | U-ESD | |
| ESD cases performed | 0 | 43 | 414 | 1000 |
| Surgery required for SMIC, recurrence or complications | ||||
| SMIC | 79 | 72 | 62 | 52 |
| LR-SMIC | 27 | 20 | 11 | 0 |
| HR-SMIC | 52 | 52 | 52 | 52 |
| SMIC suspected, but not present | 12‡ | 0 | 0 | 0 |
| Lesion recurrence | 1 | 1 | 1 | 0 |
| Complications | 2 | 2 | 5 | 10 |
| Total | 94 | 75 | 68 | 62 |
| Cost, US$ millions | 4.33 | 4.22 | 5.24 | 6.91 |
*Rounded to nearest whole number.
†ESD performed on all lesions containing the following: non-granular surface pattern, pit pattern V, Paris c component, non-lifting sign.
‡Only applicable to WF-EMR strategy where lesions categorised as highly suspicious of SMIC following optical assessment are referred for surgery (equivalent lesions triaged to ESD in selective strategies).
ESD, endoscopic submucosal dissection; HR-SMIC, high-risk submucosal invasive cancer; JGES, Japanese Gastroenterological Endoscopy Society; LR-SMIC, low-risk submucosal invasive cancer; S-ESD, selective ESD; SMIC, submucosal invasive cancer; U-ESD, universal ESD; WF-EMR, wide-field endoscopic mucosal resection.