Key studies of colorectal ESD in East Asia and the West
| Authors | Study type | Attempted lesions/mean size (mm)/mean procedure time (min) | Proximal (%)/distal (%)/rectal distribution | SMIC (%) | Per cent of cohort potentially cured of LR-SMIC | Overall en bloc (%)/R0 (%)/recurrence (%) | Perforation (%)/Postprocedure bleeding (%) |
| East Asia | |||||||
| Saito et al (2010)34 | Multicentre cohort | 1111/35/116 | 46.0/23.7/30.3 | 19.2 | 10.0 | 88/89/NS | 4.9/1.5 |
| Lee et al (2013)32 | Single-centre cohort | 874/26.5/54 | 50.0/29.3/20.7 | 15.1 | 8.4 | 97.1/90.5/0.4 | 6.1/0.5 |
| Nakajima et al (2013)18 | Multicentre cohort | 816/NS/96 | 27.3/36.4/36.3 | 18.8 | 10.8 | 94.5/80.6/NS | 2.0/2.2 |
| Niimi et al (2010)49 | Single-centre cohort | 310/28.9/NS | 27.1/46.8/26.1 | 17.1 | 11.9 | 90.3/74.5/2 | 4.5/1.3 |
| Nishiyama et al (2010)33 | Multicentre cohort | 204/27.4/NS | 39.2/36.3/24.5 | 6.9 | 4.4 | 86.8/77.5/0 | 9.8/1.0 |
| Europe | |||||||
| Probst et al (2012)36 | Single-centre cohort | 76 of 82/45.5/176 | 0/13.4 (sigmoid)/86.6 | 18.4 | 1.3 | 81.6/69.7/9.2 | 1.3/7.9 |
| Rahmi et al (2014)37 | Multicentre cohort | 45/35/110 | 0/0/100 | 6.7 | 4.4 | 64/53/7 | 18%/13% |
| Repici et al (2013)38 | Single-centre case series | 40 of 51/46.8/86.1 | 0/0/100 | 5.0 | 5.0 | 90.0/80/2.5 | 2.5/5.0 |
ESD, endoscopic submucosal dissection; LR-SMIC, submucosal invasive cancer; NS, not stated; SMIC, submucosal invasive cancer.