IBS-SSS | Overall | FMT | Placebo | P values |
n | 51 | 25 | 26 | |
At inclusion (mean (SD)) | 343.39 (86.61) | 341.68 (95.02) | 345.04 (79.56) | 0.892 |
First month (mean (SD)) | 250.49 (114.39) | 273.67 (113.86) | 228.24 (112.67) | 0.167 |
Third month (mean (SD)) | 251.57 (123.73) | 287.14 (118.30) | 218.96 (121.87) | 0.061 |
Sixth month (mean (SD)) | 263.47 (131.41) | 297.73 (130.58) | 230.70 (126.35) | 0.087 |
Difference between inclusion and first month (mean (SD)) | −93.53 (105.38) | −65.00 (91.52) | −120.92 (112.19) | 0.063 |
Difference between inclusion and third month (mean (SD)) | −90.67 (100.22) | −52.45 (97.72) | −125.71 (90.85) | 0.012* |
Difference between inclusion and sixth month (mean (SD)) | −79.53 (114.34) | −41.86 (84.24) | −115.57 (128.83) | 0.029* |
IBS-QoL | Overall | FMT | Placebo | P values |
n | 51 | 25 | 26 | |
At inclusion (mean (SD)) | 41.07 (14.98) | 42.07 (14.75) | 40.11 (15.42) | 0.646 |
First month (mean (SD)) | 30.06 (17.40) | 33.90 (17.86) | 26.38 (16.47) | 0.132 |
Third month (mean (SD)) | 28.20 (17.16) | 33.93 (18.81) | 22.94 (13.89) | 0.028* |
Sixth month (mean (SD)) | 29.50 (19.31) | 35.61 (19.47) | 23.66 (17.64) | 0.036* |
Difference between inclusion and first month (mean (SD)) | −10.89 (11.33) | −7.23 (10.31) | −14.40 (11.34) | 0.025* |
Difference between inclusion and third month (mean (SD)) | −12.06 (10.81) | −7.22 (10.12) | −16.50 (9.60) | 0.003* |
Difference between inclusion and sixth month (mean (SD)) | −10.73 (15.60) | −5.53 (12.29) | −15.70 (17.02 | 0.027* |
FMT, faecal microbiota transplantation; IBS-QoL, IBS-specific quality of life; IBS-SSS, IBS-severity scoring system.