Table 4

Association of surgical resection versus non-resection with demographic and clinical parameters for patients with pancreatic cancer in population-based registries estimated by multivariable logistic regression

ParameterUSA
(n=86 466)*
The Netherlands
(n=19 114)
Belgium
(n=7276)
Norway
(n=6178)
Denmark
(n=3005)
Slovenia
(n=2435)
Estonia
(n=1122)
OR (95% CI)†OR (95% CI)OR (95% CI)OR (95% CI)OR (95% CI)OR (95% CI)OR (95% CI)
Year of diagnosis 1.01 (1.01 to 1.02) 1.15 (1.13 to 1.17)1.01 (0.98 to 1.04)0.98 (0.95 to 1.01) 1.14 (1.03 to 1.26)1.04 (1.00 to 1.09)1.01 (0.88 to 1.16)
Sex
 Female1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)
 Male0.97 (0.93 to 1.01)1.02 (0.91 to 1.15)1.08 (0.91 to 1.27)1.18 (0.95 to 1.46)1.10 (0.82 to 1.47)0.99 (0.74 to 1.32)1.05 (0.65 to 1.68)
Age group
 <60 years1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)
 60–69 years 0.84 (0.80 to 0.89) 0.76 (0.64 to 0.89) 0.72 (0.57 to 0.91)0.82 (0.61 to 1.09)0.71 (0.45 to 1.13)0.82 (0.56 to 1.19)1.14 (0.58 to 2.25)
 70–79 years 0.59 (0.56 to 0.63) 0.37 (0.32 to 0.44) 0.43 (0.34 to 0.54) 0.44 (0.33 to 0.59) 0.56 (0.35 to 0.88) 0.46 (0.32 to 0.67)0.63 (0.32 to 1.22)
 ≥80 years 0.16 (0.15 to 0.17) 0.03 (0.03 to 0.04) 0.08 (0.06 to 0.12) 0.05 (0.04 to 0.08) 0.15 (0.09 to 0.26) 0.05 (0.03 to 0.09) 0.08 (0.03 to 0.19)
Tumour location
 Pancreas head1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)
 Pancreas body 0.65 (0.60 to 0.70) 0.49 (0.38 to 0.64) 0.60 (0.43 to 0.83) 0.52 (0.35 to 0.78) 0.22 (0.12 to 0.41)0.77 (0.47 to 1.27)0.92 (0.43 to 1.95)
 Pancreas tail 1.99 (1.85 to 2.14) 1.47 (1.17 to 1.86)1.07 (0.78 to 1.47) 1.70 (1.16 to 2.50) 2.46 (1.36 to 4.47) 0.49 (0.28 to 0.87) 3.18 (1.20 to 8.45)
 Other‡ 0.67 (0.63 to 0.71) 0.63 (0.51 to 0.78) 0.46 (0.38 to 0.56) 0.15 (0.12 to 0.20) 0.59 (0.39 to 0.89) 0.29 (0.20 to 0.41)0.60 (0.30 to 1.20)
cTNM stage§
 I–II1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)
 III 0.12(0.11 to 0.13) 0.05 (0.04 to 0.06) 0.12 (0.09 to 0.15) 0.12 (0.08 to 0.19) 0.05 (0.04 to 0.07) 0.18 (0.12 to 0.29) 0.06 (0.03 to 0.13)
 IV 0.03 (0.03 to 0.03) 0.01 (<0.01 to 0.01) 0.02 (0.01 to 0.02) 0.03 (0.02 to 0.04)NE 0.06 (0.04 to 0.08) 0.01 (<0.01 to 0.01)
  • *Numbers in table heads indicate numbers of cases available for analyses after excluding the missing.

  • †ORs and 95% CIs for surgical resection versus non-resection were calculated using multivariable logistic regression models adjusting for year of diagnosis, sex, age group, tumour location and cTNM (clinical TNM) stage. ORs shown in bold are statistically significant.

  • ‡Other: pancreas duct, overlapping lesion, NOS and other specified parts.

  • §For USA, Norway and Estonia, TNM stage is a combination of clinical and pathological stages.

  • NE, not estimable due to small case number; TNM, tumour, node, metastasis.