MB and MO patients’ baseline clinical characteristics
| MB (n=61) | MO (n=49) | P values | q | |||
| n | Baseline | n | Baseline | |||
| Anthropometry | ||||||
| Age (years) | 56 | 36.9±9.86 | 49 | 42.2±12 | 0.028 | 0.035 |
| Sex (% female) | 61 | 100 | 49 | 84 | 0.004 | 0.005 |
| Weight (kg) | 61 | 123±18 | 49 | 91.5±13.8 | 1.47E-17 | 1.33E-16 |
| BMI (kg/m²) | 61 | 45.6±5.23 | 49 | 33.2±3.8 | 1.44E-26 | 3.89E-25 |
| Fat-free mass (%) | 59 | 47.7±3.48 | 49 | 57.7±6.3 | 8.93E-16 | 4.80E-15 |
| Fat mass (%) | 59 | 49.9±3.73 | 49 | 39.4±6.6 | 4.92E-15 | 2.22E-14 |
| Trunk-fat mass (kg) | 59 | 29±4.39 | 47 | 16.9±4.4 | 6.73E-24 | 9.10E-23 |
| Leptin (ng/mL) | 58 | 78.9±28.2 | 49 | 50.7±22 | 6.89E-08 | 1.69E-07 |
| Basal metabolic rate (kg/24 hours) | 58 | 1970±315 | 21 | 1540±257 | 2.21E-07 | 4.90E-07 |
| Obesity-related diseases | ||||||
| Hypertension (%) | 61 | 69 | 49 | 0 | 5.40E-05 | 9.60E-05 |
| Dyslipidaemia (%) | 61 | 83.6 | 49 | 53 | 0.001 | 0.002 |
| Diabetes (%) | 61 | 14.7 | 49 | 0 | 0.014 | NS |
| Glucose intolerance (%) | 61 | 37.7 | 49 | 24.5 | 0.022 | NS |
| Biology | ||||||
| Total cholesterol (mmol/L) | 61 | 4.78±1.01 | 49 | 5.3±0.8 | 0.003 | 0.004 |
| HDL-cholesterol (mmol/L) | 61 | 1.15±0.35 | 49 | 1.4±0.36 | 7,40E-05 | 0.00013 |
| LDL-cholesterol (mmol/L) | 61 | 3.08±0.89 | 49 | 3.3±0.76 | 0.07 | 0.07 |
| Triglycerides (mmol/L) | 61 | 1.22±0.49 | 49 | 1.3±0.83 | NS | NS |
| Glycaemia (mmol/L) | 61 | 5.42±1.31 | 49 | 5.22±0.39 | NS | NS |
| Insulin (mUI/L) | 60 | 22.3±15.7 | 49 | 8.9±4.3 | 4.23E-12 | 1.43E-11 |
| HOMA-IR | 56 | 5.4±4.57 | 56 | 1.17±0.56 | 7.40E-17 | 4.99E-16 |
| Glucose AUC (mmol/L 120 min) | 19 | 898±199 | 40 | 799±135 | 0.06 | 0.07 |
| Insulin AUC (mUI/L 120 min) | 12 | 10800±5230 | 39 | 4560±2860 | 1.80E-05 | 3.70E-05 |
| Adiponectin (µg/mL) | 59 | 4.45±1.74 | 49 | 14.1±6.28 | 1.90E-14 | 7.58E-14 |
| Adipocyte volume (pL) | 59 | 874±194 | 49 | 684±140 | 4.30E-08 | 1.17E-07 |
| ALAT (IU/L) | 61 | 26.5±16.1 | 48 | 29.5±15.1 | 0.046 | 0.056 |
| ASAT (IU/L) | 61 | 25.4±7.63 | 48 | 29.1±17.6 | 0.45 | 0.47 |
| IL6 (pg/ml) | 58 | 4.6±2.25 | 49 | 2.08±2 | 1.72E-10 | 5.16E-10 |
| CRP (mg/L) | 57 | 8.73±6.17 | 49 | 5.01±5.67 | 2.00E-05 | 4.00E-05 |
Statistical tests performed: t-test, Mann-Whitney test and χ2 test, adapted to the variable distribution; Benjamini-Hochberg method, used for multiple testing adjustments (q).
ALT, alanine aminotransferase; AST, aspartate transminase; AUC, area under the curve; BMI, body mass index; CRP, C reactive protein; HDL, high density lipoprotein; HOMA-IR, homeostatic model assessment insulin resistance; IL6, interleukin-6; LDL, low density lipoprotein; MB, Microbaria; MO, MICRO-Obes.