Table 2

Patient demographics, Helicobacter pylori status and diagnosed neoplasia by OLGA stage, at enrolment (T0) and at the end of the follow-up (T1)

2011–2013: 1755 patients at enrolment (initial endoscopy/biopsy=T0)					2013–2016: patients at the end of the follow-up (T1)
OLGA stage	Patients	H. pylori status (%)			Clinical follow-up (1615 stage 0–I, and 29 stage II, III and IV patients) 1644 patients M:F=0.81 Mean age=51.9 (r: 18–88) Mean FU (months)=53.6 (r: 11.5–73.0) Person-years=7351.8 Clinical information obtained from general practitioners, and/or occasional gastroenterology consultation, and hospital discharge charts				Neoplasia
		H. pylori-positive	H. pylori-eradicated subjects	H. pylori-negative					GIST=2
0	1362 (77.6%) M:F=0.81 Mean age=50.3 (r: 18–84)	431 (31.6)	103 (7.6)	828 (60.8)					GIST=2
I	253 (14.4%) M:F=0.80 Mean age=59.4 (r: 25–88)	118 (46.6)	49 (19.4)	86 (34.0)					Schwannoma=1
					Endoscopy/biopsy follow-up (111 patients)				Neoplasia at the final endoscopy
						H. pylori-positive (%)	H. pylori-eradicated subjects (%)	H. pylori-negative (%)	Neoplasia at the final endoscopy
II	88 (5%) M:F=0.83 Mean age=61.6 (r: 33–82)	21 (23.9)	49 (55.7)	18 (20.5)	70/88 M:F=0.89 Mean age=62.7 (r: 35–82) Mean FU (months)=38.6 (r: 5.9–64.3) Person-years=224.9	0	59 (84.3)	11 (15.7)	LG-IEN=0 HG-IEN=0 GC=0
III	37 (2.1%) M:F=0.85 Mean age=63.6 (r: 40–81)	22 (59.5)	15 (40.5)	0	32/37 M:F=0.6 Mean age=64.4 (r: 40–78) Mean FU (months)=35.5 (r: 15.8–60.7) Person-years=94.6	0	32 (100)	0	LG-EN=3 (M:F=1:2) (1/3 enrolled as stage IV) HG-IEN=0 GC=1 (M)
IV	15 (0.9 %) M:F=1.1 Mean age=70 (r: 61–86)	11 (73.3)	4 (26.7)	0	9/15 M:F=2 Mean age=67.7 (r: 61–76) Mean FU (months)=39.4 (r: 23.3–58.1) Person-years=27.9	1 (11.1)	8 (88.9)	0	LG-IEN=1 HG-IEN=1 (M) GC=1 (M)

FU, follow-up; GC, gastric adenocarcinoma; GIST, GI stromal tumour; HG-IEN, high-grade intraepithelial neoplasia; LG-IEN , low-grade intraepithelial neoplasia; M:F, male to female ratio; r, range.