Characteristics | Individuals diagnosed with CD | Non-IBD individuals | Individuals diagnosed with UC | Non-IBD individuals | ||||
n | % | n | % | n | % | n | % | |
Total | 24 594 | 2 547 429 | 51 822 | 4 927 119 | ||||
Gender | ||||||||
Female | 14 195 | 57.7 | 1 299 156 | 51.0 | 27 410 | 52.9 | 2 374 342 | 48.2 |
Male | 10 399 | 42.3 | 1 248 273 | 49.0 | 24 357 | 47.1 | 2 522 777 | 51.8 |
Comorbidity index | ||||||||
0 | 12 315 | 50.1 | 1 741 926 | 68.4 | 25 361 | 49.0 | 2 948 994 | 59.9 |
1–2 | 7188 | 29.2 | 510 825 | 20.1 | 14 994 | 29.0 | 1 197 925 | 24.3 |
3–4 | 2860 | 11.6 | 168 551 | 6.6 | 6467 | 12.5 | 450 197 | 9.1 |
5–6 | 1 768 | 7.2 | 106 586 | 4.2 | 3921 | 7.6 | 278 940 | 5.7 |
>7 | 463 | 1.9 | 19 541 | 0.8 | 1024 | 2.0 | 51 063 | 1.0 |
Age at IBD diagnosis (years)* | ||||||||
<40 | 13 477 | 54.8 | 1 603 750 | 62.9 | 22 105 | 42.7 | 2 369 365 | 48.1 |
40–65 | 7095 | 28.8 | 599 045 | 23.5 | 18 019 | 34.8 | 1 500 711 | 30.5 |
>65 | 4022 | 16.4 | 344 634 | 13.5 | 11 643 | 22.5 | 1 057 043 | 21.5 |
Year at IBD diagnosis† | ||||||||
1977–1984 | 2971 | 12.1 | 405 671 | 15.9 | 6935 | 13.4 | 1 092 950 | 22.2 |
1985–1994 | 4627 | 18.8 | 482 049 | 18.9 | 8672 | 16.8 | 833 817 | 16.9 |
1995–2005 | 7234 | 29.4 | 653 038 | 25.6 | 15 635 | 30.2 | 1 296 167 | 26.3 |
2005–2014 | 9 762 | 39.7 | 1 006 671 | 39.5 | 20 525 | 39.6 | 1 704 185 | 34.6 |
*Age at IBD diagnosis is age at matching for non-IBD individuals in the background cohort.
† Number of non-IBD individuals matched with patients with IBD diagnosed in the respective period. All eligible matches are chosen. A match can be matched to more than one patient with IBD.
CD, Crohn’s disease; UC, ulcerative colitis.