Table 1

HBV infection in recipients transfused with blood products from three HBsAg negative/ID-NAT negative blood donors

Donors	Donation date*	Recipients	Components’ transfusiondate	Pretransfusion/ post-transfusion date	HBV markers				Transfusion transmission
Donors	Donation date*	Recipients	Components’ transfusiondate	Pretransfusion/ post-transfusion date	HBsAg	Anti-HBc	Anti-HBs (IU/L)	HBV DNA (IU/mL)	Transfusion transmission
BD1	X-54	R1-12	RBC	NA	–	–	–	–	Excluded
BD1	2 February 2008	R1-12	18 February 2008	14 April 2014	Neg	Neg	63	Neg	Excluded
	X-33	R1-11	RBC	NA	–	–	–	–	Excluded
	13 October 2009		27 October 2009	3 March 2014	Neg	Neg	Neg	Neg	Excluded
		R1-3	FFP	NA	–	–	–	–	Possible
			7 November 2009	12 February 2014	Neg	Pos	14	Neg	Possible
	X-28	R1-10	RBC	NA	–	–	–	–	Excluded
	21 April 2010	R1-10	6 May 2010	23 April 2014	Neg	Neg	Neg	Neg	Excluded
	X-12	R1-9	RBC	4 September 2011	Neg	Neg	16	–	Excluded
	31 August 2011		5 September 2011	27 November 2013	Neg	Neg	15	Neg
		R1-8	FFP	17 September 2011	Neg	Neg	Neg	–	Excluded
			17 September 2011	20 January 2014	Neg	Neg	Neg	Neg
	X-6	R1-7	RBC	17 March 2012	Neg	Neg	Neg	–	Excluded
	27 February 2012	R1-7	17 March 2012	17 February 2014	Neg	Neg	Neg	Neg	Excluded
	X	R1-4	RBC	16 September 2012	–	–	Neg	–	Excluded
	22 August 2012		16 September 2012	20 January 2014	Neg	Neg	Neg	Neg
		R1-1	FFP	9 October 2012	Neg	Neg	Neg	–	Confirmed
			9 October 2012	4 March 2013	Pos	Pos	Neg	Pos
		R1-5	PLT	27 August 2012	Neg	Neg	Neg	–	Excluded
			27 August 2012	12 February 2014	Neg	Neg	Neg	Neg
	X+5	R1-6	RBC	21 January 2013	Neg	Neg	Neg	–	Excluded
	9 January 2013		21 January 2013	9 July 2013	Neg	Neg	Neg	–
		R1-2	FFP	12 February 2013	Neg	Neg	–	–	Confirmed
			12 February 2013	1 July 2013	Pos	Pos	Neg	1.5×10³
BD2	X-57	R2-3	FFP	3 September 2009	Neg	–	–	–	Confirmed
BD2	20 August 2009	R2-3	3 September 2009	15 March 2016	Pos	Pos	Neg	1.6×10⁹	Confirmed
	X-45	R2-11	FFP	13 September 2010	Neg	–	–	–	Excluded
	9 August 2010	R2-11	13 September 2010	8 March 2015	Neg	Neg	Neg	–	Excluded
	X-24	R2-4	RBC	16 May 2012	Neg	–	–	–	Confirmed
	3 May 2012		16 May 2012	15 November 2017	Pos	Pos	Neg	Pos
		R2-9	FFP	18 May 2012	Neg	–	–	–	Excluded
			25 May 2012	14 October 2015	Neg	Neg	Neg	–
	X-21	R2-8	RBC	19 August 2012	Neg	–	–	–	Excluded
	6 August 2012	R2-8	19 August 2012	21 December 2016	Neg	Neg	34	–	Excluded
	X-4	R2-7	FFP	6 March 2014	Neg	–	–	–	Excluded
	20 January 2014	R2-7	9 March 2014	14 March 2016	Neg	Neg	Neg	–	Excluded
	X	R2-5	RBC	16 May 2014	Neg	Neg	Neg	–	Excluded
	5 May 2014		16 May 2014	2016	Neg	Neg	Neg	Neg
		R2-1	FFP	30 July 2014	Neg	Neg	Neg	–	Confirmed
			6 August 2014	17 April 2015	Pos	Pos	Neg	6×10⁷
		R2-6	PLT	NA	–	–	–	–	Excluded
			8 May 2014	7 August 2015	Neg	Neg	32	Neg
	X+3	R2-2	FFP	24 October 2014	Neg	Neg	Neg	–	Probable
	21 August 2014	R2-2	10 November 2014	22 March 2016	Neg	Pos	467	Neg	Probable
BD3	X-21	R3-7	PLT	26 February 2014	–	Neg	52	–	Excluded
BD3	27 February 2014	R3-7	4 March 2014	5 May 2014	–	–	–	Neg	Excluded
	X-8	R3-6	RBC	8 April 2015	Neg	Neg	Neg	–	Excluded
	24 March 2015		9 April 2015	7 August 2016	Neg	Neg	Neg	–
		R3-8	PLT	25 March 2015	–	Neg	Neg	–	Excluded
			26 March 2015	21 April 2015	Neg	–	–	Neg
	X-4	R3-5	RBC	22 July 2015	Neg	Neg	Neg	–	Excluded
	15 July 2015	R3-5	29 July 2015	28 June 2016	Neg	Neg	Neg	–	Excluded
	X	R3-9	RBC	22 October 2015	Neg	Pos	45	–	Excluded
	18 November 2015		25 November 2015	5 May 2017	Neg	Pos	18	Neg
		R3-1	FFP	21 February 2016	Neg	Neg	–	–	Probable
			22 February 2016	8 July 2016	Pos	Pos	Neg	1.4×10⁸
		R3-4	PLT	12 November 2015	Neg	Neg	139	–	Excluded
			19 November 2015	18 October 2016	Neg	Neg	182	Neg
	X+4	R3-2	RBC	14 March 2016	Neg	–	–	–	Probable
	22 March 2016		24 March 2016	28 September 2016	Pos	Pos	Neg	6×10⁵
		R3-3	PLT	6 October 2015	Neg	Neg	–	–	Excluded
			23 March 2016	31 May 2016	Neg	Neg	Neg	Neg

Bold values indicate transfusion transmission cases.
*Months from index donation.
BD, blood donor; FFP, fresh frozen plasma; HBsAg, HBV surface antigen; ID, individual donation; NA, not applicable; NAT, nucleic acid testing; Neg, negative; PLT, platelet; Pos, positive; RBC, red blood cell.