Table 9

Use of nitrous oxide and oxygen gas, intravenous sedation and intravenous analgesia

SCEACDifference (one-sided 97.5% CI)Non-inferiority margin or one-sided P value
Nitrous oxide and oxygen gas
 Global291 (32.9%)283 (31.9%)−1.0% (−∞ to 3.3%)10%
 Non-BCSP209 (43.5%)180 (36.4%)−7.0% (−∞ to −0.9%)10%
 BCSP82 (20.4%)103 (26.2%)5.9% (−∞ to 11.7%)10%
Intravenous sedation
 Global591 (66.9%)586 (66.1%)−0.8% (−∞ to 3.6%)10%
 Non-BCSP349 (72.6%)357 (72.3%)−0.3% (−∞ to 5.3%)10%
 BCSP242 (60.1%)229 (58.3%)−1.8% (−∞ to 5.0%)10%
Intravenous analgesia
 Global582 (65.8%)588 (66.3%)0.5% (−∞ to 4.9%)10%
 Non-BCSP342 (71.1%)360 (72.9%)1.8% (−∞ to 7.4%)10%
 BCSP240 (59.6%)228 (58.0%)−1.5% (−∞ to −5.3%)10%
  • BCSP, Bowel Cancer Screening Programme; EAC, EV-assisted colonoscopy; SC, standard colonoscopy.