Table 5

The LASSO-derived predicted probability in percentage (with 95% prediction intervals) of T1 CRC within an LNPCP based on location, white light features and NBI features

Proximal locationDistal location
Homogeneous granularGranular with large noduleGranular with non-granular erythematous areaNon-granularHomogeneous granularGranular with large noduleGranular with non-granular erythematous areaNon-granular
Hiroshima A–BBleeding
Depressed area −1.9
(0.3–3.7)
2.5
(0.5–5.6)
2.6
(0.5–5.6)
2.8
(0.5–5.7)
2.8
(0.7–5.3)
3.8
(0.8–8.6)
3.9
(1.0–8.4)
4.2
(1.0–8.4)
Depressed area +1.8
(0.2–4.2)
2.5
(0.4–6.7)
2.6
(0.4–6.5)
2.8
(0.4–6.8)
2.8
(0.6–5.6)
3.7
(0.6–9.9)
3.8
(0.7–9.5)
4.1
(0.9–9.7)
Bleeding
+
Depressed area −4.5
(0.6–12.7)
6.0
(0.9–16.2)
6.1
(0.9–17.3)
6.6
(0.9–18.5)
6.6
(1.3–15.7)
8.8
(1.7–21.1)
9.0
(1.8–21.4)
9.7
(1.8–22.9)
Depressed area +4.4
(0.4–13.8)
5.9
(0.8–18.8)
6.1
(0.7–19.5)
6.5
(0.7–20.2)
6.5
(1.2–17.0)
8.7
(1.4–24.5)
8.8
(1.5–23.6)
9.5
(1.6–25.4)
Hiroshima C1Bleeding
Depressed area −9.7
(1.9–23.2)
12.8
(4.1–26.0)
13.0
(3.9–25.2)
14.0
(4.3–26.5)
13.9
(3.0–30.3)
18.1
(5.6–37.3)
18.4
(5.9–36.2)
19.6
(6.8–37.4)
Depressed area +9.5
(1.7–22.8)
12.6
(3.2–27.9)
12.8
(3.3–25.8)
13.8
(3.5–27.4)
13.7
(11.8–67.0)
17.8
(4.6–41.3)
18.2
(5.1–37.5)
19.4
(5.7–38.9)
Bleeding
+
Depressed area −20.8
(3.6 –51.3)
26.4
(7.9–54.7)
26.9
(7.7–55.6)
28.5
(7.5–58.8)
28.4
(7.6–59.1)
35.1
(13.1–64.2)
35.6
(13.1–64.7)
37.5
(13.7–66.3)
Depressed area +20.5
(3.4–50.0)
26.1
(6.3–56.7)
26.5
(6.5–54.5)
28.1
(6.4–57.0)
28.0
(7.0–59.2)
34.7
(10.6–65.4)
35.2
(11.4–65.1)
37.1
(11.8–67.0)
Hiroshima C2Bleeding
Depressed area −34.1
(8.5–74.2)
41.4
(12.9–80.3)
42.0
(13.2–77.9)
43.9
(14.8–77.0)
43.8
(15.2–81.0)
51.6
(18.9–87.2)
52.2
(20.5–85.6)
54.1
(24.3–83.9)
Depressed area +33.7
(8.5–73.7)
41.0
(11.9–80.5)
41.6
(13.2–77.2)
43.5
(14.6–76.5)
43.4
(15.9–79.2)
51.2
(18.7 - 86.3)
51.7
(21.3–83.8)
53.7
(23.0–83.5)
Bleeding
+
Depressed area −55.9
(17.3–88.8)
63.4
(25.6–91.4)
64.0
(26.2–91.2)
65.8
(27.9–91.1)
65.7
(31.0–91.7)
72.3
(37.7–93.9)
72.8
(40.0–93.1)
74.3
(43.1–93.1)
Depressed area +55.5
(19.1–88.4)
63.0
(26.4–91.7)
63.6
(27.8–91.1)
65.4
(28.5–91.3)
65.3
(32.9–91.5)
72.0
(38.8–94.2)
72.4
(41.6–93.2)
74.0
(44.2–93.5)
Hiroshima C3Bleeding
Depressed area −64.3
(23.1–94.3)
71.1
(32.5–95.2)
71.6
(32.3–94.6)
73.2
(38.6–95.8)
73.1
(34.4–96.0)
78.8
(40.8–97.2)
79.2
(42.0–96.9)
80.5
(46.2–97.3)
Depressed area +63.9
(25.6–94.5)
70.8
(32.5–95.8)
71.3
(34.2–95.7)
72.9
(39.6–96.3)
72.8
(37.7–96.5)
78.5
(40.8–97.5)
78.9
(44.3–97.4)
80.2
(49.4–97.7)
Bleeding
+
Depressed area −81.6
(40.0–98.0)
85.8
(51.5–98.5)
86.1
(52.5–98.4)
87.0
(54.4–98.5)
87.0
(59.1–98.6)
90.1
(65.1–98.9)
90.3
(66.1–98.9)
91.0
(68.1–99.0)
Depressed area +81.3
(44.4–98.0)
85.6
(51.4–98.5)
85.9
(54.2–98.4)
86.8
(57.1–98.7)
86.8
(60.9–98.6)
90.0
(65.3–99.1)
90.2
(67.0–99.0)
90.8
(70.9–99.2)
  • Bleeding indicates spontaneous bleeding (–: absence; +: presence).

  • Bootstrap-based 95% prediction intervals are provided (based on the percentile method). These cannot be interpreted in the classical sense of a 95% CI; they merely represent an indication of the level of uncertainty surrounding the reported estimates, due to the relatively small dataset and complex estimation procedures.

  • CRC, colorectal cancer; LASSO, least absolute shrinkage and selection operator; LNPCP, large non-pedunculated colorectal polyp.