Table 1

Clinical studies on the development and restoration of the infant microbiome

Intervention/Follow-up up without intervention	ClinicalTrials.gov Identifier	Participant enrolment
Antibiotics at birth	NCT02477423	80
Antibiotics in preterm	NCT02784821	420
At-birth restoration with vaginal fluids	NCT03298334	800
Diet supplementation—eggs	NCT03385252	662
Diet supplementation—sweet potato vs pear	NCT03229863	120
Diet supplementation—Human milk fortifier	NCT03214822	30
Diet supplementation-maternal—Omega-3	NCT03297801	109
Diet supplementation—protein sources	NCT02142647	40
Human milk donor	NCT02573779	125
Probiotic/prebiotic supplemented formula	NCT03320837	108
Probiotics	NCT03388112	30
Probiotics B. breve	NCT03219931	320
Probiotics in preterm	NCT02197468	60
Probiotics in preterm	NCT02695784	40
Rotavirus vaccine	NCT03031743	88
Rotavirus vaccine	NCT02220439	76
Skin-to-skin contact	NCT03181269	88
Follow-up without intervention	NCT03001167, NCT02121938, NCT03365583, NCT03236194, NCT01789268, NCT02778750, NCT02526004, NCT02843087, NCT03229967, NCT01661491, NCT03235635, NCT03296631, NCT03396198, NCT02836119, NCT03335202, NCT02061306, NCT03213275, NCT03373721	Variable