Univariate analysis of potential histological and endoscopic factors associated with colorectal neoplasia
| Variables | Number (%) | HR (95% CI) | P value |
| Cumulative inflammatory burden (median, IQR) | |||
| Endoscopic* | 10.2 (5.7–15.1) | 1.8 (1.4 to 2.4) | <0.001 |
| Histological* | 11.6 (7.2–16.0) | 2.0 (1.5 to 2.8) | <0.001 |
| Macroscopic features of chronicity | |||
| Scarring only | 537 (54.4) | 2.6 (1.5 to 4.4) | <0.001 |
| Tubular, featureless or shortened colon | 318 (32.2) | 3.6 (2.2 to 5.9) | <0.001 |
| Postinflammatory polyps | 447 (45.3) | 2.6 (1.7 to 3.9) | <0.001 |
| Stricture | 46 (4.7) | 5.9 (2.4 to 14.5) | <0.001 |
| Procedure type | |||
| White-light (ref) | 6543 (86.1) | 1 | |
| Chromoendoscopy | 1056 (13.9) | 2.5 (1.5 to 4.1) | <0.001 |
| Inadequate colonoscopy | |||
| On preceding examination (n, %) | 434 (5.9) | 2.0 (1.0 to 3.9) | 0.05 |
| Mean (median, range) | 0.0 (0.0–1.0) | 5.2 (1.6 to 17.4) | 0.01 |
| Mean number of biopsies (median, IQR) | 9 (7–10) | 1.2 (1.1 to 1.3) | <0.001 |
| Mean surveillance interval (year; median, IQR) | 2.1 (1.5–26.5) | 0.91 (0.89 to 0.94) | <0.001 |
*HR per 10-unit increase in cumulative inflammatory burden (equivalent of 10, 5 or 3.3 years of continuous mild, moderate or severe active disease, respectively). Statistically significant variables are highlighted in bold.