Collisson | Moffit | Bailey | |
Approach | Microarray | Microarray | Expression analysis (RNAseq and microarray) |
Cohort | 63 primary resected PDAC | 145 primary resected and 61 metastatic PDAC tumours | 96 RNAseq and 242 microarray primary patient samples |
Tumour/stromal contribution | Microdissection | Multivariate analysis (virtual microdissection) | Macrodissection |
Tumour subtypes | Classical | Classical | Pancreatic progenitor |
Immunogenic | |||
Exocrine-like | ADEX | ||
QM | Basal like | Squamous | |
Stromal subtypes | Not assessed | Activated | ESTIMATE |
Normal |
This pancreatic cancer subtype table is adapted from refs 40–42.
ADEX, Aberrantly Differentiated Endocrine eXocrine; ESTIMATE, Estimation of STromal and Immune cells in MAlignant Tumor tissues using Expression data; PDAC, pancreatic ductal adenocarcinoma; QM, quasimesenchymal.