Table 1

Molecular subtyping of patients with pancreatic cancer

ApproachMicroarrayMicroarrayExpression analysis (RNAseq and microarray)
Cohort63 primary resected PDAC145 primary resected and 61 metastatic PDAC tumours96 RNAseq and
242 microarray primary patient samples
Tumour/stromal contributionMicrodissectionMultivariate analysis (virtual microdissection)Macrodissection
Tumour subtypesClassicalClassicalPancreatic progenitor
QMBasal likeSquamous
Stromal subtypesNot assessedActivatedESTIMATE
  • This pancreatic cancer subtype table is adapted from refs 40–42.

  • ADEX, Aberrantly Differentiated Endocrine eXocrine; ESTIMATE, Estimation of STromal and Immune cells in MAlignant Tumor tissues using Expression data; PDAC, pancreatic ductal adenocarcinoma; QM, quasimesenchymal.