Table 2

Relationship between paired pre-CRT/post-CRT ctDNA status and pCR in 144 patients where both results are available

pCRNon-pCR
Pretreatment ctDNA positive, n/total n (%)
 Post-CRT ctDNA positive1/21 (5)11/91 (12)
 Post-CRT ctDNA negative20/21 (95)80/91 (88)
Pretreatment ctDNA negative, n/total n (%)
 Post-CRT ctDNA positive0/8 (0)0/24 (0)
 Post-CRT ctDNA negative8/8 (100)24/24 (100)
  • CRT, chemoradiation; ctDNA, circulating tumour DNA; pCR, pathological complete response.