Table 4

Risk of gastric cancer by risk score and risk category

Risk scoreTotal numberGastric cancer*
No. (%)
Risk category†Total number‡
No. (%)
Gastric cancer*
No. (%)
Number needed to screen§
Derivation cohort9838 (100.0)267 (2.7)37
 02060 (0.0)Low (0–11)6564 (66.7)78 (1.2)84
 11070 (0.0)
 2510 (0.0)
 32480 (0.0)
 48577 (0.8)
 54915 (1.0)
 63451 (0.3)
 76394 (0.6)
 8109912 (1.1)
 991713 (1.4)
 1083220 (2.4)
 1177216 (2.1)
 1268724 (3.5)Medium (12–16)2715 (27.6)120 (4.4)23
 1377526 (3.4)
 1462231 (5.0)
 1536719 (5.2)
 1626420 (7.6)
 1728328 (9.9)High (>16)559 (5.7)69 (12.3)8
 1814118 (12.8)
 19526 (11.5)
 204912 (24.5)
 21254 (16.0)
 2281 (12.5)
 2410 (0.0)
Validation cohort5091 (100.0)138 (2.7)37
 01231 (0.8)Low (0–11)3352 (65.8)42 (1.3)80
 1460 (0.0)
 2190 (0.0)
 31331 (0.8)
 44243 (0.7)
 52562 (0.8)
 61842 (1.1)
 73023 (1.0)
 853212 (2.3)
 95127 (1.4)
 104294 (0.9)
 113927 (1.8)
 1237615 (4.0)Medium (12–16)1460 (28.7)65 (4.5)22
 1344311 (2.5)
 1431717 (5.4)
 1517910 (5.6)
 1614512 (8.3)
 1713016 (12.3)High (>16)279 (5.5)31 (11.1)9
 18765 (6.6)
 19322 (6.3)
 20223 (13.6)
 21124 (33.3)
 2241 (25.0)
 2430 (0.0)
  • *The prevalence rate of gastric cancer.

  • †In both derivation and validation cohorts, there is a significant difference in prevalence of gastric cancer across the three risk categories (p<0.001).

  • ‡Proportion relative to all participants of the derivation or validation cohort.

  • §Defined as the number of participants who should undergo gastroscopy screening to identify one patient with gastric cancer.