Table 1

Characteristics of patients at baseline*

Glutamine (n=54)Placebo (n=52)
Characteristic
Age–years32.4±9.530.9±7.1
Sex—no. (%)
 Female37 (68.5)37 (71.2)
 Male17 (31.5)15 (28.9)
Ethnic group—no. (%)
 White44 (81.4)41 (78.9)
 Black5 (9.3)6 (11.5)
 Hispanic3 (5.6)3 (5.8)
 Asian2 (3.7)2 (3.9)
 Other00
IBS-SS301±54302±58
Stool frequency (no./day)5.4±2.35.3±2.2
Stool consistency (Bristol stool form scale)6.5±0.66.6±0.6
Intestinal permeability
(Lactulose/mannitol ratio)0.11±0.030.11±0.04
  • Patients in the glutamine group included 30 patients from Site 1 and 24 patients from Site 2.

  • Patients in the placebo group included 24 patients from Site 1 and 28 patients from Site 2.

  • *Plus-minus values are means±SD. There were no significant differences between the two groups.

  • IBS-SS, Irritable Bowel Syndrome Severity Scoring System.