Table 1

Overview of radiographic criteria used in currently available cross-sectional imaging studies to detect fibrostenosis in patients with stricturing Crohn’s disease. All studies use histopathology as a reference standard

Study IDRadiographic modalityRadiographic criteria assessed for stricture detectionCriteria required for stricture diagnosis
Prestenotic dilation
(mm)
Luminal narrowing
(mm)
Wall thickening
(mm)
Ultrasound (US)Baumgart et al 14 Ultrasound elasticity imaging
>3 mm
Not further specified
Kumar et al 15 SICUS Wall thickening
Maconi et al 16 TUS
>25 mm
✔ Markedly narrowed lumen
>4 mm
All criteria required
Onali et al 17 SICUS
<10 mm
Luminal narrowing
Pallotta et al 18 SICUS
>25 mm

<10 mm
Luminal narrowing
Ripollés et al 19 CEUS Not further specified
Serra et al 20 CEUS
>4 mm
All criteria required
Stidham et al 21 US elasticityNot indicatedNot indicatedNot indicatedNot further specified
Wilkens et al 22 CEUS Not further specified
CTAdler et al 23 CT enterography
≥3 mm
Not further specified
Chiorean et al 24 CT enteroclysis
Luminal narrowing ≤50%
Luminal narrowing
Pellino et al 26 PET/CT
>3 mm
Not further specified
Vogel et al 25 CT enterography
>3 cm

<10 mm

>5 mm
Luminal narrowing and wall thickening
MRIKumar et al 15 MR enterography Not further specified
Li et al 27 MT-MRINot indicatedNot indicatedNot indicatedNot further specified
Pellino et al 26 PET/MR
>3 mm
Not further specified
Pous-Serrano et al 28 MR enterographyNot indicatedNot indicatedNot indicatedNot further specified
Punwani et al 29 MR enterography Not further specified
Rimola et al 30 MR enterography✔ Luminal narrowing ≤50%Luminal narrowing ≤50% and prestenotic dilation
Sinha et al 34 MR enterography
>3 mm
Not further specified
Steward et al 35 MR enterography Not further specified
Tielbeek et al 31 MR enterography diffusion-weighted MRI Not further specified
Wagner et al 32 Diffusion-weighted MRI Not further specified
Wilkens et al 22 Dynamic contrast-enhanced MR enterography Not further specified
Zappa et al 33 MR enterography
>1.5 of normal loop
Not further specified
  • CEUS, contrast-enhanced ultrasound; MT, magnetisation transfer; PET, positron emission tomography; SICUS, small intestinal contrast ultrasonography; TUS, transabdominal ultrasonography; US, ultrasound.